Hedi Raizer
Journal
6,180 articles
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Exercise Delays Ovarian Aging in Humans and Mice
Cross-sectional analyses of more than 150,000 participants show an association between higher physical activit...
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mRNA-LNP Therapeutics for Obesity: Weight Loss with Metabolic Repair
Obesity involves dysfunction in metabolic tissues that is not always fully corrected by weight loss. An mRNA-l...
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Glycoconjugate Strategy for GLUT-Driven Curcumin Delivery in Breast Cancer Cells
Researchers synthesized glycoconjugate vanadyl complexes to target glucose transporters (GLUTs) in malignant c...
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Benchmarking Boltz Co-Folding Models for GPCR Drug Discovery
Researchers benchmarked Boltz, a state-of-the-art co-folding model, using ligand-bound human G protein-coupled...
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On the generalization and usability of cofolding models for GPCR drug discovery
The generalizability of co-folding models for protein–ligand structure prediction remains unclear. Here, we be...
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New Paradigm of q-CAR Drug Development Targeting Disease-Specific Protein Conformations
This review introduces quantitative conformation-activity relationship (q-CAR) to address limitations of stati...
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New paradigm of q-CAR drug development targeting disease-specific protein conformations
Drug discovery has progressed to using advanced AI-driven platforms. These systems rely heavily on static stru...
- A permeable protein nanocage enables facile cargo loading and cytosolic protein delivery Cytosolic delivery of therapeutic proteins remains a challenge in drug delivery. Here, the authors report the...
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Oral nonpeptide GLP-1 receptor agonist VCT220 for obesity treatment: a randomized, double-blind, phase II trial
VCT220 is a novel nonpeptide, orally available glucagon-like peptide-1 receptor agonist (GLP-1RA) designed to...
- Walmart Recalls Marketside Tomato Bisque Soup Kit Walmart is recalling 3,240 packages of its Marketside brand tomato bisque soup kit across 29 states due to pot...
- How Long Should a Woman Aged 30+ Be Able to Hold a Wall Sit? A woman aged 30 or older should be able to hold a strict wall sit for about 45 to 60 seconds as a practical ba...
- Abdominal Obesity and Vitamin D Deficiency Synergize Mortality Risk A large study of more than 5,500 adults over 50 found a striking combination of risk factors: abdominal obesit...
- Abdominal Obesity and Vitamin D Deficiency Synergize Mortality Risk A large study of more than 5,500 adults over 50 found a striking combination of risk factors: abdominal obesit...
- Vitamin D Deficiency and Abdominal Obesity Increase Mortality Risk A large study of more than 5,500 adults over 50 found a striking combination of risk factors: abdominal obesit...
- Abdominal Obesity and Vitamin D Deficiency Synergize Mortality Risk A large study of more than 5,500 adults over 50 found a striking combination of risk factors: abdominal obesit...
- Abdominal Obesity and Vitamin D Deficiency Synergize Mortality Risk A large study of more than 5,500 adults over 50 found a striking combination of risk factors: abdominal obesit...
- This common vitamin deficiency becomes far more dangerous when paired with belly fat A large study of more than 5,500 adults over 50 found a striking combination of risk factors: abdominal obesit...
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Can Walking Count Toward Your Weekly Mileage During Marathon Training?
Run coaches explain if you should swap your easy run for a walk.