Hedi Raizer
Journal
6,180 articles
- Untitled BackgroundMicrowave ablation (MWA) is an organ-preserving minimally invasive option for symptomatic benign thy...
- Universal versus risk-factor-based screening for gestational diabetes mellitus: findings from a large-scale co Gestational diabetes mellitus (GDM) carries significant feto-maternal risks. Early diagnosis and treatment eff...
- NR5A1 Gene Variants: Variable Phenotypes, New Variants, and Genotype-Phenotype Correlations Introduction NR5A1 variants are among the most frequent monogenic causes of disorders of sex development (DSD)...
- Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): A Multisystem Disorder MASLD affects approximately one-third of adults worldwide and is increasingly recognized as a multisystem diso...
- Bone Marrow Adipoq-Lineage Cells: Identities, Functions, and Mechanisms Bone marrow Adipoq-lineage cells refer to all cells that have ever expressed Adipoq (Adiponectin) and their pr...
- Differential regulation of neutrophil degranulation by p38 MAPK and mitochondrial ROS during Mycobacterium lep Erythema Nodosum Leprosum (ENL) is an inflammatory complication of leprosy associated with peripheral nerve da...
- Overcoming Translational Barriers for Natural Bioactive Peptides Bioactive peptides from natural sources exhibit potent antimicrobial, antihypertensive, antioxidant, and antic...
- Effects of herbal medicines and their phytoconstituents on vagus nerve stimulation: a systematic review of in The vagus nerve regulates autonomic, inflammatory, metabolic, and neurobehavioral functions. Although invasive...
- Absorption, distribution, metabolism, and excretion of [14C]SH-1028, a third-generation EGFR-TKI, in rats and SH-1028 is an irreversible third-generation epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-T...
- Gut Microbiota and the Gut–Liver Axis in MASLD: Mechanisms, Immune Regulation, and Therapeutic Opportunities Metabolic dysfunction-associated steatotic liver disease (MASLD) is one of the most common chronic liver disea...
- A novel redox signalling axis mediates nicotine-induced podocyte injury Nicotine has been shown to induce Nlrp3 inflammasome activation, thereby contributing to podocyte injury. The...
- Role of PCSK9 in breast cancer: a systematic review of its mechanistic pathways and clinical relevance IntroductionBreast cancer is a heterogeneous disease in which accurate classification based on biomarker expre...
- Untitled Mitochondria play a central role in cellular metabolism, not only by generating ATP through oxidative phosphor...
- Efficient experimental characterization of the GPCRome via deep receptor scanning Here, the authors introduce deep receptor scanning methodology to enable characterization of 940 human GPCRs i...
-
Alignment with experimental data improves protein generative modeling
Direct preference optimization (DPO) aligns a pretrained protein language model with experimental stability da...
- Evolutionary Origins of Enantioselectivity in Plant Borneol Dehydrogenases Researchers investigated how natural evolution creates new functionalities in plant borneol dehydrogenases usi...
- Anti-inflammatory and Anti-mitotic Properties of Donepezil in Primary Keratinocytes and T Cells The non-neuronal acetylcholine system in skin produces anti-inflammatory effects beneficial for conditions lik...
-
Crystal Structures Reveal Half-Open ssDNA Binding Mode of E. coli Topoisomerase III
Five crystal structures at high resolution show a previously unrecognized half-open ssDNA-binding mode in Esch...