Hedi Raizer
Journal
6,180 articles
- TogoPhosTAC as a delivery-ready platform for targeted protein dephosphorylation This study presents togoPhosTAC, a biologic platform that directs engineered phosphatases to target proteins f...
- TogoPhosTAC as a delivery-ready platform for targeted protein dephosphorylation This study presents togoPhosTAC, a biologic platform that directs engineered phosphatases to target proteins f...
- Evolutionary Conservation Analysis Reveals Primordial Function of STING as Lipid Metabolism Regulator STING is a well-known activator of type I interferon responses, but its ancestral function remains debated. Th...
- TogoPhosTAC as a delivery-ready platform for targeted protein dephosphorylation This study presents togoPhosTAC, a biologic platform that directs engineered phosphatases to target proteins f...
- Eradication of MRSA biofilm-associated implant infections by low-immunogenic sustained-release lysostaphin fused to thermosensitive polypeptides Authors present an antimicrobial characterisation of their elastin-like polypeptide-fused lysostaphin, which o...
- Effects of Bitter Almond Gum on Glycemic Control and Oxidative Stress in Women with Type 2 Diabetes Mellitus Type 2 diabetes mellitus (T2DM) is marked by hyperglycemia, oxidative stress, and systemic inflammation. Prebi...
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Addressing barriers to using fixed-dose combination antihypertensive medications: lessons from the Million Hearts initiative
- Knowledge Distillation and Incremental Learning for Osteoporosis Detection on Knee X-ray Images Osteoporosis reduces bone mass in elderly populations, increasing fracture risk. This study proposes an automa...
- Untitled Type 2 diabetes mellitus (T2DM) is marked by hyperglycemia, oxidative stress, and systemic inflammation. Prebi...
- Eradication of MRSA biofilm-associated implant infections by low-immunogenic sustained-release lysostaphin fused to thermosensitive polypeptides Authors present an antimicrobial characterisation of their elastin-like polypeptide-fused lysostaphin, which o...
- Untitled Pyrethroid insecticides like deltamethrin pose significant risks to non-target organisms due to widespread use...
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Physical activity delays ovarian aging in part through adiponectin-related signaling pathways
Physical activity has geroprotective properties, yet its role in ovarian aging is incompletely understood. Her...
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Aligning protein-generative models to experimental fitness with ProteinDPO
This Article demonstrates that direct preference optimization (DPO) can be used to effectively align an unsupe...
- Synergistic Regenerative and Anti-Inflammatory Effects of Ponesimod and Amniotic Epithelial Stem Cells in Cuprizone Model Human amniotic epithelial cells release neurotrophic factors that may support tissue repair. This study invest...
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Aligning protein-generative models to experimental fitness with ProteinDPO
This Article demonstrates that direct preference optimization (DPO) can be used to effectively align an unsupe...
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Design, Synthesis, Molecular Modelling and Biological Evaluation of Oxiconazole-Based 1,2,3-Triazoles as Dually Acting Antifungal and Antitu
The rise of azole-resistant fungal infections in immuno-compromised cancer patients emphasizes the need for st...
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Short- and long-term shifts in food purchasing behaviours and nutrition disparities in the USA during and after the COVID-19 pandemic
Using US household grocery data from 2017–2022, Hu et al. find that lockdowns temporarily shifted purchases to...
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Histological aging signatures for monitoring tissue-specific aging and disease
Whole-slide histopathological images from 40 tissue types reveal morphological changes associated with aging,...