Hedi Raizer
Journal
6,180 articles
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Structure of human cytoplasmic Pol II complex explains global transcription repression by GDOWN1
The assembly and nuclear import of RNA polymerase II (Pol II) are not fully understood. Here, the authors iden...
- Native yeast kinetochore structures identify an essential inner kinetochore interaction Accurate kinetochore assembly at centromeres is essential for proper chromosome segregation. Here, the authors...
- Characterization of Acute Kidney Injury Induced by Cecum Ligation and Puncture Model Sepsis-associated acute kidney injury remains incompletely understood, with experimental models varying in sev...
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Immune Cell Migration in Tumors and Inflammation: Molecular Mechanisms and Therapeutic Targets
Cancer and inflammatory diseases depend on dynamic interactions between pathological tissues and the host immu...
- Characterization of Acute Kidney Injury Induced by Cecum Ligation and Puncture Model Sepsis-associated acute kidney injury (SA-AKI) is a serious complication in critically ill patients and contri...
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Therapeutic Approach to Cardiovascular-Kidney-Metabolic Syndrome
The authors discuss screening across the lifespan, lifestyle interventions, and guideline-directed medical the...
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Plant-Based Dietary Patterns and Breast Cancer Risk: A Systematic Review and Meta-Analysis
This systematic review and meta-analysis evaluated the relationship between breast cancer incidence and three...
- Development and Validation of a Food Frequency Questionnaire for Caffeine Intake in Iranian Adolescents Adolescent caffeine consumption is increasingly common and may pose potential health risks. However, there is...
- Development and validation of a food frequency questionnaire for caffeine intake and dietary assessment in Iranian adolescents Adolescent caffeine consumption is increasingly common and may pose potential health risks. However, there is...
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More muscle, less belly fat: mutations to a gene are linked to wide-ranging benefits
Analysis of one million diverse genomes yields mutations associated with lower risk of diabetes, heart disease...
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FNIP1 variants are associated with favourable metabolism in 1 million humans
The FNIP1 pathway has a role in human energy metabolism, and its inhibition is a potential therapeutic strateg...
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A covalent PFKL activator suppresses tumor growth
An electrophile–drug conjugate covalently activates PFKL through K677 engagement and releases a selective CPT2...
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Palmitate promotes liver metastases by decreasing neutrophil antitumour behaviour
DHHC17-mediated palmitoylation stabilizes laminin-511 in the liver metastatic niche, which decreases the cance...
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Switching off the FNIP1 gene protects against metabolic disease
People with ultra-rare variants of the FNIP1 gene have a favourable metabolic profile.
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More muscle, less belly fat: mutations to a gene are linked to wide-ranging benefits
Analysis of one million diverse genomes yields mutations associated with lower risk of diabetes, heart disease...
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TMEM135 Deficiency Prevents Intestinal Lipid Accumulation via ELOVL6-PPARα Activation
This study reveals that TMEM135 deficiency enhances lipid absorption and utilization in the intestine, address...
- Structure of human cytoplasmic Pol II complex explains global transcription repression by GDOWN1 The assembly and nuclear import of RNA polymerase II (Pol II) are not fully understood. Here, the authors iden...
- Native yeast kinetochore structures identify an essential inner kinetochore interaction Accurate kinetochore assembly at centromeres is essential for proper chromosome segregation. Here, the authors...