Hedi Raizer
Journal
6,204 articles
- Full-fat dairy may be healthier than conventional advice has suggested A 12-week study found no meaningful increases in weight, body fat, cholesterol, or insulin resistance among ad...
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Distinct Amyloid-β Filament Fold in APP Flemish Mutation
Brain samples from individuals with the rare APP Flemish mutation reveal a distinct amyloid-β filament fold th...
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Structure-based scaffold hopping reveals strategies to overcome oncogenic KIT and PDGFRA mutation-driven drug-resistance in GIST
In this work, the authors develop and characterize KIT/PDGFRA inhibitors to define key molecular interactions...
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Structure-based macrocyclization of alpha-ketoamides yields potent coronavirus protease inhibitors
Viral proteases are key targets for developing direct-acting antivirals to combat infections like SARS-CoV-2....
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Flemish APP Mutation Drives Distinct Amyloid-β Fold
Cryogenic electron microscopy reveals that the rare Flemish mutation in the amyloid-β precursor protein drives...
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α-Synuclein blocks endoplasmic reticulum co-translational protein translocation early in Parkinson’s disease
Proteomic and transcriptomic profiling on hiPSC-derived midbrain dopaminergic neurons with pathological α-synu...
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CLOCK/BMAL1 interactome uncovers homeodomain factors as tissue regulators
Aygenli et al. map chromatin-bound CLOCK/BMAL1 protein complexes across three mouse tissues and uncover PROX1,...
- Chrono-atlas of Cell-Type Specific Daily Gene Expression Rhythms in the Regenerating Colon How tissues maintain circadian rhythms during regeneration remains poorly understood. Here, the authors genera...
- Lucilia sericata larval secretions modulate fibroblast responses under oxidative stress This study evaluated dose-dependent effects of Lucilia sericata larval secretion on 3T3 fibroblast behavior in...
- Regional diversity of cranial skeletal stem cells governs BMP-2 mediated bone regeneration Cranial skeletal stem cells exhibit location-dependent gene activity and regenerative potential, with distinct...
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Haemolytic Injury and Cardiovascular Disease
Plasma free haemoglobin from haemolysis induces haemodynamic dysregulation and cardiovascular injury through n...
- Clozapine-Induced Hypertriglyceridemia Linked to Liver Sinusoidal Endothelial Cell Defenestration This study investigates the link between clozapine-induced hypertriglyceridemia and liver sinusoidal endotheli...
- AI-designed antibodies with Germinal Center Dynamics for Enhanced Specificity and Affinity Maturation Recent advancements in artificial intelligence have enabled the design of antibodies that mimic germinal cente...
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MBNL depletion drives stem cell fusion and immature myonuclear states in myotonic dystrophy type 1
This study shows that muscle stem cells fuse with existing muscle fibres in myotonic dystrophy type 1, produci...
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Visual Food-Cue Processing in Pregnant Women With Gestational Diabetes
Treviño Montemayor, Lesniara-Stachon et al. investigate visual food-cue processing in late pregnancy in women...
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Social inequalities linked to accelerated biological aging
Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the...
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Untitled
Malnutrition is frequent in maintenance hemodialysis (MHD). We aimed to validate the Global Leadership Initiat...
- Chrono-atlas of cell-type specific daily gene expression rhythms in the regenerating colon How tissues maintain circadian rhythms during regeneration remains poorly understood. Here, the authors genera...