Hedi Raizer
Journal
6,180 articles
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An AI-enabled structural atlas decodes kinase specificity across the human proteome
Phosphorylation potential and kinase specificity are assigned for the entire human proteome.
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Sequential reading of a stepwise-shortened peptide immobilized on nanopore
A nanopore-based ‘chop and measure’ method sequences peptides at single-amino-acid resolution by using enzymat...
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Mitochondrial Quality Control: Mechanisms and Therapeutic Targets
Mitochondria regulate metabolism, apoptosis, and redox balance; dysfunction contributes to numerous human dise...
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Short ACE2 Isoform Upregulated in Adipose Tissue from Women with Obesity
A novel short ACE2 isoform lacking the SARS-CoV-2 binding domain was recently identified in human respiratory...
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Deciphering the role of histidine in cancer
A new study reveals histidine as a readily measurable and potentially modifiable metabolic biomarker for cance...
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Miniaturizing and modifying natural proteins with Raygun
Probabilistic sequence encoding from language model embeddings within a generative AI framework enables protei...
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Rational design of disordered proteins for sequence–function investigation
GOOSE enables the design and testing of thousands of disordered protein region sequences to reveal distinct se...
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Property guidance for protein sequence generative models with ProteinGuide
On-the-fly conditioning of pretrained protein generative models guides protein generation toward specific prop...
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Midsole Support Plate Material Effects on Lower-Limb Kinetics During Basketball Movements
This study investigated whether midsole support plate material alters lower-limb biomechanics during common ba...
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Mitochondrial Quality Control Mechanisms and Therapeutic Targets
Mitochondria regulate metabolism, apoptosis, and redox balance; dysfunction contributes to numerous diseases....
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Genomic, Epigenomic and Transcriptomic Regulation of Cellular Senescence
Senescence is a complex, dynamic cell state shaping ageing biology and tissue homeostasis. This review examine...
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Senotypes define the diverse landscape of senescent cells
This Perspective proposes a senotype framework for classifying senescent cells by their origins, molecular fea...
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Bioengineering strategies to interrogate and modulate the aging immune system
Nikolich et al. highlight immunoengineering approaches including advances in extracellular matrix and biomater...
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Short-chain fatty acids
This Review provides an overview of the biology of short-chain fatty acids, with a focus on their synthesis, s...
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Urinary Metabolomic Profiling Identifies Impact of Whole Grain, Vegetable, and Fruit Intake in Healthy Adolescents
A plant-based diet is reportedly effective in preventing chronic and metabolic diseases, primarily because of...
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Transcriptomic profiling of human brown and white adipose tissue depots
White and brown adipose tissues play opposing roles in energy storage and expenditure. Here, the authors show...
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Short-chain fatty acids
This Review provides an overview of the biology of short-chain fatty acids, with a focus on their synthesis, s...
- Transcriptomic Profiling of Human Brown and White Adipose Tissue Depots White and brown adipose tissues play opposing roles in energy storage and expenditure. Here, the authors show...