Hedi Raizer
Journal
6,180 articles
- Nostalgia for Early 2000s Fashion Trends and Cultural Memory A cultural retrospective examines how early 2000s fashion trends and sensory memories evoke nostalgia, reflect...
- 20 Years Later, Body Positivity Remains Central A personal narrative explores how body positivity shifted from a niche club experience to a broader cultural m...
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Phosphoantigen-driven dissociation of butyrophilin oligomers activates γδ T cells
Γδ T cells represent a promising avenue for cancer immunotherapy. The Vγ9Vδ2 T-cell receptor (TCR), which is e...
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Mechanism of K63-linked Polyubiquitin Recognition and Cleavage by the BRCA1-A Complex
The authors show that ARISC–RAP80 binds K63-linked ubiquitin chains through multiple subunits and non-catalyti...
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A ubiquitin chain-feeding mechanism for BRCA1-A
The BRCA1-A complex cleaves K63-linked polyubiquitin chains at DNA damage sites to control DNA repair. Here, t...
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Structure of NHE6 and Its Lipid-Mediated Interactions Regulating Endosomal pH
The sodium-proton exchanger NHE6 localises to endosomal membranes and mutations in the protein are known to ca...
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PA200 modulates immunoproteasome structure and activity
Proteasomes help cells recycle proteins and shape immune responses. Here, the authors show that PA200 binds st...
- Integrative structural analysis of human endosomal NHE6 reveals a lipid-associated gate and disordered C-terminus The endosomal Na+ /H+ exchanger HsNHE6 regulates organellar pH and is implicated in neurological disease. Here...
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How ocean enzymes are providing access to understudied cannabinoids
The berberine-bridge-like (BBE-like) enzyme family catalyzes diverse chemical transformations, including the f...
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PA200 modulates immunoproteasome structure and activity
Proteasomes help cells recycle proteins and shape immune responses. Here, the authors show that PA200 binds st...
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Blood metabolomic signatures linking air pollution to lung cancer in the Cancer Prevention Studies
Exposure to ambient air pollution is an established risk factor for lung cancer. In here, the authors report m...
- A flexible repertoire of wound closure strategies precedes whole-body regeneration Animals capable of whole-body regeneration can heal virtually any wound. Here they show that Hofstenia miamia...
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Uncovering the role of chromatin organization and dynamics in heart disease
Two studies published in Science explore how 3D chromatin organization and structure can influence cardiac dev...
- Chronic Conditions and Aortic Disease Risk: Prospective Cohort Study This study shows that multimorbidity and several chronic conditions, including cardiovascular, respiratory and...
- A humanized anti-TNFR1 nanobody antagonist targeting the CRD3 region suppresses inflammation and necroptosis in vitro Humanized TNFR1-targeting nanobodies selectively block inflammatory and necroptotic signaling in vitro, offeri...
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A modular self-assembling peptide platform targeting TGF-β1 for tendon regeneration
Excessive TGF-β1 activity contributes to tendon degeneration and fibrosis. Here, authors develop a self-assemb...
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Triglyceride–glucose index, neutrophil-to-lymphocyte ratio, and high-sensitivity C-reactive protein across albuminuria stages in type 2 diab
Diabetic kidney disease is a major microvascular complication of type 2 diabetes mellitus. This study evaluate...
- Adipose-Derived Regenerative Cells Attenuate Diminished Ovarian Reserve in a Rat Model Diminished ovarian reserve involves reduced oocyte quantity and quality, leading to endocrine dysfunction. Thi...