Hedi Raizer
Journal
6,180 articles
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Structural mechanism governing the directionality of bridge recombination
Cryo-electron microscopy structures show how IS621 bridge recombinase mediates DNA excision, explaining its na...
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Designing non-natural RNA-guided nucleases
Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the...
- Structure and Mechanism of Human Sphingosine-1-Phosphate Transporter MFSD2B Sphingosine-1-phosphate (S1P) is a potent lipid signaling molecule. The authors determine cryo-EM structures o...
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Carbon Source–Driven Metabolic Remodeling Defines Phenomic States in Lipomyces starkeyi
Researchers collected multi-omic data to dissect how carbon source availability reshapes the metabolic network...
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Designing non-natural RNA-guided nucleases
Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the...
- Structural Molecule-Associated Protein Changes in SUMO1-Deficient Mice Associated with Attenuated Age-Related Anxiety-Like Behavior SUMO1 is essential for normal neural function, yet its role in age-related behavioral changes remains unclear....
- Nuclear Aging in Polyglutamine-Induced Neurodegeneration Machado-Joseph disease is an autosomal dominant neurodegenerative disorder caused by a CAG over-repetition in...
- Untitled Highland soil environments represent ecologically dynamic habitats that may harbor metabolically versatile and...
- Metabolic Heterogeneity in Adipocytes Treated with BT2 Kinase Inhibitor Researchers investigated how BT2, a branched-chain α-ketoacid dehydrogenase kinase inhibitor, affects sphingol...
- Structure and Mechanism of Human Sphingosine-1-Phosphate Transporter MFSD2B Sphingosine-1-phosphate (S1P) is a potent lipid signaling molecule. The authors determine the cryo-EM structur...
- TDP-43 controls RNA structure through high affinity lattice interactions TDP-43 is an essential RNA-binding protein. Here, the authors show how it binds single-stranded poly(UG) RNA t...
- IL-2 Mutein-Engrafted Antibody MHS552 Selectively Expands Functional Regulatory T Cells Although low-dose IL-2 therapy has shown promise in treating autoimmune and inflammatory conditions by support...
- Alginate attenuates reactive microglia in vivo Alginate is a marine polysaccharide commonly used in the form of hydrogel in different biomedical applications...
- Concomitant ablation of SOS1 and SOS2 triggers lethal phenotype The RAS guanine nucleotide exchange factors Son of Sevenless 1 and 2 (SOS1 and SOS2) are key regulators of RAS...
- IL-2 Mutein-Engrafted Antibody MHS552 Selectively Expands Functional Regulatory T Cells Although low-dose IL-2 therapy has shown promise in treating autoimmune and inflammatory conditions by support...
- IL-2 Mutein-Engrafted Antibody MHS552 Selectively Expands Functional Regulatory T Cells Although low-dose IL-2 therapy has shown promise in treating autoimmune and inflammatory conditions by support...
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Adolescent Weight Gain Trajectories Linked to Biological Aging: Genetically Informed Study
High body mass index in adolescence is associated with accelerated biological aging and may predict obesity-re...
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Cathepsin D-Driven IL2RG-JAK2 Signal Hijacking Disrupts Hepatic Insulin Action
Hepatic insulin resistance, an early feature of prediabetes, plays a pivotal role in disrupting glucose homeos...