Hedi Raizer
Journal
6,180 articles
- A-type proanthocyanidins from Spenceria ramalana alleviate inflammation through dual inhibition of iNOS and COX-2 expression and catalytic a This study investigates the potent anti-inflammatory potential and underlying dual-inhibition mechanism of two...
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Characterization of Key Odorants in Three Black Tea Cultivars Using Sensomics and Molecular Docking
High-quality black tea is globally prized for its characteristic aromas, notably floral and sweet notes. The t...
- Structural basis of fatty acid activation and transport by human FATP2 Here, the high resolution cryo-EM structures of human FATP2 in both the pre-catalytic and intermediate states,...
- Design, One-Pot Green Synthesis, Computational Studies, and Biological Evaluation of Novel Pyran-Pyridine Hybrids for Targeting MCF-7 Breast This study reports a catalyst-free, one-pot synthesis of novel pyran-pyridine hybrids (4a–j). The target compo...
- Structural determinants for FAT10 activation and transfer from UBA6 to E2 enzymes Cryo-EM captures FAT10 activation and transfer from UBA6 to E2 UBE2Z, revealing FAT10 monopolises UBA6. Effici...
- Decay of the Lef1-Srsf3-MicroRNA Axis Impairs DNA Damage Response Researchers identify the transcription factor Lef1, splicing regulator Srsf3, and DNA damage response microRNA...
- Cysteine Preconditioning Enhances Post-Freeze-Thaw Proliferative Capacity of Human Synovial Mesenchymal Stem Cells Synovial mesenchymal stem cells are promising for cartilage regeneration, but freeze–thaw injury can reduce th...
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How the discovery of mammalian regeneration shapes translational efforts
This Journal Club highlights the landmark study that provided the first evidence of regeneration in mammals, d...
- TMEM189/PEDS1 Deficiency Aggravates MASH Progression via FASN-Mediated Macrophage Activation Transmembrane protein 189 (TMEM189), also known as plasmanylethanolamine desaturase 1 (PEDS1), is involved in...
- Peripheral Autonomic Dysfunction and Vascular Mechanics in Non-Diabetic Hypertensive Patients: A Pilot Study Using Electrochemical Skin Cond The clinical significance of peripheral autonomic dysfunction in assessing cardiovascular risk in non-diabetic...
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Formylpeptide receptor activation attenuates renovascular remodeling in neurogenic hypertension
Formylpeptide receptor agonism with Compound 17b lowers blood pressure, restores vascular function, and revers...
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Obesity-associated unfolded protein response, oxidative stress, and NRF2 signaling
This review examines molecular mechanisms of NRF2 activation in obesity, focusing on bidirectional crosstalk w...
- Handgrip Strength Not Independently Associated With Steatosis in People With MASLD Reduced handgrip strength (HGS) is considered a surrogate marker of whole-body muscle strength and has been as...
- Untitled Open-weight large language models (LLMs) can be deployed locally at low cost, making them attractive for patie...
- Optimizing Kidney Protection in Type 1 Diabetes While treatments for non-diabetic and type 2 diabetic CKD have advanced significantly, no new drugs have been...
- TyHGB Predicts Mortality in Critically Ill Heart Failure Patients This study evaluated the association between triglyceride–high-density lipoprotein cholesterol–glucose–body ma...
- Leadership for the postdoctoral to independent investigator transition The transition from postdoctoral researcher to independent investigator is marked by complex decision-making a...
- Transcriptome Profile of Peripancreatic Adipose Tissue in Pancreatitis Chronic pancreatitis involves extensive fibrosis that impairs exocrine and endocrine function, with obesity as...