Ten-year comparative outcomes of one-anastomosis gastric bypass versus single-anastomosis duodeno-ileal bypass as revisional procedures afte
A substantial proportion of patients have insufficient weight loss or clinically significant weight regain after sleeve gastrectomy and require revisional surgery. One-anastomosis gastric bypass and single-anastomosis du
Long-term weight and metabolic outcomes following revisional surgery after sleeve gastrectomy have been studied in a recent retrospective cohort study. The authors compared 10-year weight, metabolic, nutritional, and safety outcomes of one-anastomosis gastric bypass (OAGB) and single-anastomosis duodeno-ileal bypass (SADI-S) performed as conversion procedures for weight recurrence after sleeve gastrectomy. A total of 90 patients underwent revisional surgery, with 47 undergoing OAGB and 43 undergoing SADI-S. The study found that 10-year weight and BMI outcomes were comparable between the two groups. However, SADI-S achieved higher percentage excess weight loss (EWL) and percentage total weight loss (TWL) at 5 years compared to OAGB. Lipid profiles were also more favorable after SADI-S, with lower total cholesterol and triglycerides at multiple time points. In contrast, several micronutrient levels were higher after OAGB, including calcium, zinc, vitamin D, and folate at multiple time points. Comorbidity outcomes and overall complication rates were similar between the two groups, with no mortality observed during follow-up. These findings suggest that while both OAGB and SADI-S may offer comparable long-term weight and metabolic outcomes, SADI-S may have a slight edge in terms of lipid profile improvements and micronutrient levels. However, the study's retrospective design and limited sample size should be interpreted with caution, and further research is needed to confirm these findings.